Repressed Expression of the Human Xanthine Oxidoreductase Gene

Regulation of the Human Xanthine Oxidoreductase Gene

Expression and Regulation of Human Xanthine Oxidoreductase

Yliopistopaino The truth is rarely pure and never simple.

The thermodynamics of xanthine oxidoreductase catalysis.

Xanthine oxidoreductase is a complex enzyme found in a wide range of organisms. Recent interest in this enzyme stems from its ability to produce reactive oxygen species under a range of conditions. It is found as a homodimer, each unit containing a molybdopterin cofactor, two iron sulfur centers, and FAD. The enzyme can exist in two forms that differ primarily in their oxidizing substrate speci...

Human xanthine oxidoreductase: in search of a function.

The molybdoenzyme, xanthine oxidoreductase (XOR), has been much studied, largely because of its ready availability on a large scale from cows' milk [ l ] . It catalyses the oxidation of a wide range of substrates, most notably hypoxanthine and xanthine, generating xanthine and uric acid respectively, in the process of purine catabolism. The enzyme is a homodimer of 150 kDa subunits and exists i...

Human xanthine oxidoreductase determination by a competitive ELISA.

1 Human Xanthine Oxidoreductase Determination by a Competitive ELISA Maria Giulia Battelli and Silvia Musiani .............................................. 3 2 Simultaneous Determination of Polyunsaturated Fatty Acids and Corresponding Monohydroperoxy and Monohydroxy Peroxidation Products by HPLC Richard W. Browne and Donald Armstrong ..................................... 13 3 Determination of...